As far as velocity vs weight: I don't subscribe to caliber wars. Get what you can control. The rest is about shot placement.
However, I do want to state that I would probably pass on the Hydra-Shoks unless you're getting a really good deal on them (free). Otherwise, they're old technology (1985!) and there are better rounds out there.
I prefer the Federal Tactical HST 124gr +P JHP. Or the Speer Gold Dot 124gr. I want to try the 147gr +P HST next and the Gold Dots in +P varieties. I'm very good with the Gold Dots, but the +P HSTs are quite snappy and I'm still getting used to them.
If you want to do a little research on why you might want to pass on the Hydra-Shok, here is some great reading material.
http://9x19mm.com/forum/viewtopic.php?t=456(Pay particular attention to posts by "Snowman366" - he gives some really convincing first-hand accounts.)
http://frag.110mb.com/http://findarticles.com/p/articles/mi_m0BTT/is_168_28/ai_112685770/pg_1?tag=artBody;col1http://ammo.ar15.com/project/Self_Defense_Ammo_FAQ/index.htm(Halfway down the page there is a summary of Federal HS vs HST. Be sure to also follow the links to the Wound ballistics workshop articles which were good reads too).
Great quote from this article:
Quote:There are a lot of people who pick a load without adequately researching the ammo they trust their life on. The Federal Hydra-Shock is one such example. It was the whiz-bang bullet of its time, but has since been eclipsed by many other bullet designs. The principal weakness of that round are its lack of expansion after passing through clothing.
Whatever you choose, by 3 boxes - keep one to carry and shoot the other 2! Repeat at least once a month, pending finances.